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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5900e87aa91d739cd31942e525c5da2e6b1f62f0d11e20a884c4c2c80be79a' 
  AND token = 'erUQjlompHxPmve6+LpWk95mWR9GDlitnETaWZU6/4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}