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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4539911b4dbbb925d69a159565fd1840efe6909731d2a5fdf4b1844526c1093' 
  AND token = 'TbZSIo20JEHX20ZNCmAc+qM9R2CLiyLWOU9X/9gUWBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}