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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '769ecd6cbc730e5acc4b397866cabc346411efbcaa8bea15a821615b3c926fdb' 
  AND token = 'l6Hp8mn8g6y4Wnq91qToukvMR4u8F7VAuCUJrbzGfzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}