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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72a1999cdbe1e4e51eb2e9c677851c9a62922c78cd8178dd53ebeb8789f4ed0' 
  AND token = '0vF6w3khdH7EaC18FugvzBjSjfpPiBhm4UB3xFiowG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}