SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3f8e2c4073f43d0d6a014dbc75609a8a612b76e77069415b3b2c8b0744a7074' 
  AND token = 'QjQkWz0WdAI5U3xT9JWnDz+zxGUFzQR/FhLOvxeSAjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}