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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0b8c1c47bb5e7cb22561dca8ac2409177d30d6d92beb4a64f4726530fe52fb' 
  AND token = 'e8n3LRjpksj6bUmcAQiYs4xBWhGRKe9k2UMUmZURdW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}