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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49011c8aeee7bf80310c6f1c025343159c4dd54b9b538de0edd2c06c22ae6608' 
  AND token = 'd8RNuySZcj572c1Zum3j7zXyN9Leby/sDDK7u+n5lyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}