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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '025e9f1afe204dd561a2b30eb2e214a4c952ca0ed3c92b6cf332627720816634' 
  AND token = '4ZoVPD4c6lQB+gSk+hxvxxOQlwOVUvC4vRY58BelZF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}