SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58073347e475ac30d54d4e00e180cb1085f10e461d3be2ba09ba8cb05982fec2' 
  AND token = 'uRHF/0r+HfoRz/Rmw/kWP8fyJOU47FkjIfDTo+FlzgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}