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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66bb8cb1817e347a0e2c12473019701c24e2a3199adfecf176ce157836cb671' 
  AND token = 'GyZCaxYJbYG4oh1msSo/dX+MoGGcR+jt5CuOnlwrf8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}