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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '812c084bad3d29628d44f9f3005c46ed074b6bc330d57b2aa482fa3cac7f8b93' 
  AND token = 'fSYq6mwPg4tt8pF0xoQhtHiNARfQ5GxqbQFMJe17WlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}