SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90de2f4035591188cf67b1fdaa1890b1f760c14bb820f1763304eb16c13ec906' 
  AND token = 'zXNuMThvxraylF9F73mUMHrfTh9WCEq7bKBMNyKt8Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}