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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c69ef7e90555d1263cad35c74de269cacad1b86d7a11af1fc80a9de8765b6b13' 
  AND token = '+g+ZD3EN1u1QpTb+jVxBA7E3NLyZUKL0CAGli3fhrF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}