SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e674a93e2d0af27a57686120bcc9b81c25c3bae1d87412b6f157d157712dc10b' 
  AND token = 'L94JMDEZH1KR6s8Jnpa7hNbLtPa+PVSewCX8GkTiHKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}