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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad3174d6b6123a87cd6a3827c5a3116c9eb51fb9003e501c108ba0c6e8023fa' 
  AND token = 'oUDJYwEystTE55DEdz3OwTTfiyRgZegmehgrL+VqUvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}