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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '368c68c3ae2756ed40ffc17412e73c1b3bd84c3ac7043e24544511b9ec31ca52' 
  AND token = 'bVxUoD4HRXwFFef+irNcmaR3e8prsXmhM2oPHrXWljU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}