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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a67005a58f214c80ce8b71c1c1a288a4d1c1043bc4042043f89414d5d8c40082' 
  AND token = 'i0f/7/m0/SPtvs+zv0tfdoPBznR/y14hVnk8zVzEeuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}