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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b949eb5c84eb82ac23a9055586bf12f83c8831536e8c7a9d1c7002c674b32b2e' 
  AND token = 'fI9Nd0zgnW1uqhnyKAGHNVRpRGaUR4A37eQ1v2sjphg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}