SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aadbc48742b79c7fed46dcdb386375c587bb1bc69eab023f312b9bcab4172036' 
  AND token = 'ki96nUWD5E7IDOrum9uKutD/AuUk0TWpvmC4WiBPJgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}