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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aae0223ca53a3d10b93a71ac97dc38e77be4275b7189787d4880249fe829691' 
  AND token = 'gU1PZX3M1M1vOUtOOyGHBSv+V1CW0rIQDAMiQNZYDoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}