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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273026e9bd9165b05c90369f0c96d0f7ca85a5f4f883b5dda739d9c059b851d8' 
  AND token = 'kM80zn71rAdUxAT5Qykk7z0bh5t7e2Xy1/AIMT4sstM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}