SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35191592775b46c35f33bfd0cd8e29e86440d843f6506c902c36cc8091ca646' 
  AND token = 'kqE/dI3t/6+CaYkagyYIeIH5J01kqT6KtQJNuveAJSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}