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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8870ead4249fc3047e9132536a2beb54529eac41a350a95eaa67e3a01ab1a74' 
  AND token = 'NVz8XoBNC+1BGKDwU7uwZDirWzQXSXgogFIoUnodW9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}