SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4775a1f36e7c6afd3cb6f27840bdc124e0e3489a25ced97f1a82dab5deba45a' 
  AND token = 'Zp1mRaQgOATtLxCtWeEMa4sa4GIE6Zf55r9oegL/EzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}