SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f31b58ca012525f164caefde1724f4224768a2da8a32ea247c564698160a15' 
  AND token = '+ccqJSvGZ94fyFvtIA9a82RWcnhnFqb3Ker328XOWBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}