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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3f89caa5611c062e655815547a718cf29dd24aae4cccf45e8629a3806305a71' 
  AND token = '4+902ctrSogX3TEA/8Tx1FDO5QaRB5bkAXzIDvM8MWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}