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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb5f845ab50866d4c94f7f40b9bb5846e47c4759f6391af8d9b34f173504815' 
  AND token = 'pCXyi8sUP7X9a0XOHmeosTfFpbP/oIbKNWRCaTWsQZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}