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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba2a2a66c1d27db01610057b81e754cb7e804ae89de933e4233e166eaafc356e' 
  AND token = 'R9DPt9aX3rzxvEIRTB0u2fm6HPNwWJdiBlkpt2aqd5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}