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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0451c70c9a0cf6e9e5eae5c4bc1734332ff36a68c331957ef684b2b72c9986a4' 
  AND token = 'bPeMpj0IT4XBDUeXe3GFoXXokR9LzRA5to82cw8kfX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}