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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e4a792949dd2c6bef8a75f53da7869544bd4a6a030e8cee2d2e211f3aa13fe' 
  AND token = 'VccgbdnIL1ViXOVSM9Qfpon2+4q861/+0/JIhHoIID8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}