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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0097ad98a3eb57f60c0a558867915b812f651b81f72c3c0c3337e96f2e2c107e' 
  AND token = 'TPkldAmLK0vvBA68zlKt4lc9i1I+DwT0aAqLAnYlrc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}