SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2016a8161bd36bc07f8a3d3cc7fbf0a5408f7f55c1fc0949e4ae2ffb9921292' 
  AND token = 'qro7LTARBMahirBdL827Fa2ln7YlXb6hI1P17b0SAxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}