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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a508fe2b5c80c7d88f2c184fa41dc5c697e70e22ad53d738ebd515a0dddef4' 
  AND token = '/XZN8KTRT/KRzTpibo8fAKSZeCfXYphwhO+x/ZxVg/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}