SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1e0641fb058444062cc0f6481c0afd500fd3df83ccaddf3727ae8af1251fdf' 
  AND token = 'C2k5rh+wsRIjBUKoGkj30j02AanKRupv82+U5EFVIWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}