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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18dc4187640c2f71e798b1667600bf69f8ff8ef4ab5a1e1b50efa50d6b8e68b1' 
  AND token = 'PV0uuGsNoGSKuuC05ttVReq73sFUEaaM/AR1qgyYLZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}