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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e2b37c9f43010dc870a2be6ddf2f8780d13c6afbc418747cdc3443d56c3cd5' 
  AND token = 'nq1lIKuAKtmE8Cn3qq4e+xrrv6pWZ+5oqJjeBEURUHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}