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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd64dcec357b06c018b693fa5514fb6e860e9f9439d177f022e99121108e7065b' 
  AND token = 'REOfacikwztFRhrbYrEeFtUg73dfSXHA4THfyaeQFXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}