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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f0205cc2b62bef208a3c22f0702ab38ba39ee54b09486aa0a6ff4dca1117df' 
  AND token = '1cqU1BCpFJ+/pItptVXzPc1rPQS7Cd/g1M7zvFk1/eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}