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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e936b6afb41f6f20c4fcdf0df7889cd910e7af43aaf34131d1b9d6b927b4b50' 
  AND token = 'QHQHj5NoFsXQxcRD1AR8xR1riHBAiAP/h6R69xro2Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}