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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728fe3f63830710f2bde64707ac2c975f47c247bf9ce5ebc456887ae698c0d3c' 
  AND token = 'Nt+V8Wlvq5s7XesRkWGZDQETP4GqRdmblWln4D8gm3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}