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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dfd2d6db3db8cb057d6a8a826cdb4d1aaa3e393d1bfdabf73d42c4366a41925' 
  AND token = '0bzJrf7WK5Dx+m9UO3x4sMywSEiB+21pKEBpAU9Gi2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}