SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e59f8a8b6ea299745cf1f922600e844b550a0ab566e7f14b00228201ba3f0e' 
  AND token = 'EVNw9WCs0P6H4NTYRM9Z4AsiV5Bum60h9xd1yr2C8s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}