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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0655489298b17be4d526007cd5e87f8d8ccacdf21ec28910c3084ac270844d' 
  AND token = 'q4NM1V3uk9T8YV9V+kMp9K5z85+Lh6BRnMPuFD17Ckk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}