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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '268535a3b7acc1b3f082f4c4d6c34ecd5cd720be6a250051c044f1f435b63eb2' 
  AND token = 'taXgaARBbYEqDv+xIsuD78E6CexNs+XiPxDeD7+PwsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}