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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eefbed19fe5b201302315257736518e63ce31e7f4fb70aba5ee93e653e50cd81' 
  AND token = 'l41UV4cLd+TZoqvZC4hz8/M2UsZEOed/CEwTMdqKKhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}