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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ad10e6ac46405fd02d559607bca21482e29ad3542d067dce90348916deda56' 
  AND token = 'CXKOrj3Z/A5RxwO2H7zbShRei9rtwJtq3XpPFBR0hvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}