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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dbbcd2540e2fec9d4fd20ad70eaeb94dab5605ed88856008cf8c7f4a5a9bd0b' 
  AND token = 'qLTcVUaAE0LP2XEi8kjjiGQTJh+HjycQJvcbsK9UKqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}