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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265c9f1b94dc97fa6af521fd46bdad1fe7aa7386dbb521eea105598aa6491f46' 
  AND token = '432qKCcdjtbRcjugMOVcLtvI9qcUYBYiLz2yXq+t28w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}