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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '293b94ff65b000c2fb0f4bdc9d0326e5bdebe8b5a60776ac845aeeec3bf5a45c' 
  AND token = 'XzWbPzaGCaBX7oKOGia4tvKx5mbBelegWn9G3gvxit0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}