SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc03ae53e33ab438346006ab66bd692e0d9c0de97fec5f4b637aa08054dca8ec' 
  AND token = 'hYxIaZXeD5pu/4eZMMcwXHXw3SqyGKm4ooO1imS6k0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}